SciMed
Disposable Blade Holder for Rotary Microtome — Feather Compatible, Universal Fit, Precision Clamp
Disposable Blade Holder for Rotary Microtome — Feather Compatible, Universal Fit, Precision Clamp
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Disposable blade holder (knife holder) for rotary microtome — replacement or upgrade unit for histopathology tissue sectioning workflows using disposable Feather Brand microtome blades and equivalent standard disposable blade cassettes. Universal fit compatible with standard rotary microtome blade mount interfaces (Leica RM2125, Thermo Scientific HM325, Sakura Accu-Cut SRM 200, and our SciMed Rotary Microtome). Precision clamp holds blade at consistent set-back angle (typically 4-8°) for reproducible sectioning quality. $599.99 direct — versus $1,500-$3,500 for OEM Leica / Thermo replacement blade holders.
What's included
- 1 × Disposable blade holder (knife holder)
- User instruction card
- Note: This sale is for the HOLDER only — disposable blades not included
Compatibility
| Feather Brand blades | Fits standard Feather microtome blade cassettes (S22, S35, R35, N35 series) |
|---|---|
| Universal fit | Compatible with standard blade mount pattern on: Leica RM2125 · Thermo Scientific HM325 · Sakura Accu-Cut · SciMed Rotary Microtome · generic universal-mount microtomes |
| Set-back angle | Adjustable 4-8° typical (blade edge angle relative to cutting axis) |
| Blade removal | Quick-release clamp allows single-handed blade change |
| Autoclave | Yes (removes for pre-autoclave cleaning) |
| For non-rotary microtomes | Contact us before ordering — send us your microtome model + blade dimensions for compatibility check |
Why replace or upgrade a blade holder?
- Wear from repeated blade changes — clamp mechanism loosens over years of daily use
- Damage from dropped blade — sharp blade edge can scar clamp surface
- Corrosion from autoclave cycling — years of humidity + cleaning
- Upgrade from reusable knife to disposable blade workflow — modern pathology labs increasingly use disposable Feather-brand blades for consistent sharpness + reduced infection risk vs reusable knives that need sharpening
- Multi-microtome standardization — one blade holder type across all your microtomes for staff training simplicity
Applications
- Histopathology — paraffin-embedded tissue sectioning (H&E, IHC, special stains)
- Cytopathology — cell block sectioning
- Veterinary pathology — animal tissue diagnostic + research
- Academic gross anatomy + histology teaching — student practice + skills exams
- Forensic pathology — autopsy + medico-legal tissue examination
- Research histology — animal model tissue examination
- Pharmaceutical toxicology — safety study histology
Best for
- Hospital pathology labs (replacement + spare for daily use)
- Community + academic pathology teaching labs
- Veterinary diagnostic + reference labs
- Multi-microtome pathology facilities (standardization)
- Universities with medical / veterinary histology teaching programs
- International pathology capacity building via DDP
- NGO / global health pathology training programs
Buying for a pathology lab or teaching program?
- Volume pricing on 3+ orders — multi-microtome fleet + teaching lab standardization
- Net-30 invoicing for verified pathology labs + universities
- SAM.gov / VA compliant — VA + military pathology
- Compatible with Feather blade bulk pricing on 5+ box orders (Feather S22 blades: $85/box of 50)
- Bundle with SciMed Rotary Microtome ($1,199) — save $100 on holder when purchased together
- International DDP shipping — global pathology capacity building markets
FAQ
Does this fit my microtome brand?
Compatible with all standard rotary microtomes using universal blade holder mount (Leica RM2125, Thermo Scientific HM325, Sakura Accu-Cut SRM 200, SciMed Rotary Microtome, and generic universal-mount microtomes). For non-rotary microtomes (sledge, sliding, cryostat), send us your microtome model + a photo of your existing blade holder for compatibility verification before ordering.
Which disposable blades work?
Feather Brand microtome blades (S22, S35, R35, N35 series). Also compatible with equivalent standard disposable microtome blade cassettes from Leica, Thermo Scientific, VWR, and other manufacturers using the same universal blade dimensions.
Blade set-back angle?
Adjustable 4-8° typical (blade edge angle relative to cutting axis). Standard for paraffin sectioning: 4-6°. For hard tissue (bone, cartilage): 6-8°.
How does this compare to OEM Leica or Thermo blade holders?
Feature parity on core function — universal blade fit, precision clamp, autoclavable, angle-adjustable. Leica + Thermo have premium finish + tighter tolerance. Price differential: $599 vs $1,500-$3,500. For most clinical + teaching histology use, our unit delivers full utility at 20-40% of OEM replacement pricing.
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